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Cisplatin
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help| Cisplatin, cisplatinum or cis-diamminedichloridoplatinum(II) (CDDP) is a platinum-based chemotherapy drug used to treat various types of cancers, including sarcomas, some carcinomas (e.g. small cell lung cancer, and ovarian cancer), lymphomas and germ cell tumors. It was the first member of its class, which now also includes carboplatin and oxaliplatin. Platinum complexes are formed in cells,... Read enhanced Wikipedia article |
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Cisplatin
Cisplatin, cisplatinum or cis-diamminedichloridoplatinum(II) (CDDP) is a platinum-based chemotherapy drug used to treat various types of cancers, including sarcomas, some carcinomas (e.g. small cell lung cancer, and ovarian cancer), lymphomas and germ cell tumors. -
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Carboplatin
There are also results to show that CISplatin and CARBOplatin cause different morphological changes in MCF-7 cell lines while exerting their cytotoxic behaviour. -
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Esophageal cancer
Chemotherapy may be given after surgery (adjuvant, i.e. to reduce risk of recurrence), before surgery (neoadjuvant) or if surgery is not possible; in this case, cisplatin and 5-FU are used. -
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Cervical cancer
On June 15, 2006, the US Food and Drug Administration approved the use of a combination of two chemotherapy drugs, hycamtin and cisplatin for women with late-stage (IVB) cervical cancer treatment. -
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History of cancer chemotherapy
This accidental discovery, however, soon initiated a series of investigations and studies into the effects of platinum compounds on cell division, culminating in the synthesis of cisplatin. -
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Platinum
Cisplatin is particularly effective against testicular cancer; cure rate was improved from 10% to 85%. -
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Crosslinking of DNA
Cisplatin (cis-diamminedichloroplatinum(II)) and its derivative forms DNA cross links as monoadduct, interstrand crosslink, intrastrand crosslink or DNA protein crosslink. -
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Nicholas J. Vogelzang
The results of the trial show that tumors shrank in 41 percent of patients on pemetrexed in combination with a more commonly used chemotherapy agent called cisplatin. -
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CROP (gene)
"Effect of cisplatin treatment on speckled distribution of a serine/arginine-rich nuclear protein CROP/Luc7A.". -
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Electrochemotherapy
Presently, applications for cancer treatment have reached clinical use (antitumor electrochemotherapy using bleomycin or cisplatin).
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Cisplatin