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Di-tert-butyl dicarbonate
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help| Di-tert-butyl dicarbonate is a reagent widely used in organic synthesis. This carbonate ester reacts with amines to give N-tert-butoxycarbonyl or so-called t-BOC derivatives. These derivatives do not behave as amines, which allows certain subsequent transformations to occur that would have otherwise affected the amine functional group. The t-BOC can later be removed from the amine using acids.... Read enhanced Wikipedia article |
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Di-tert-butyl dicarbonate
Di-tert-butyl dicarbonate is a reagent widely used in organic synthesis. This carbonate ester reacts with amines to give N-tert-butoxycarbonyl or so-called t-BOC derivatives. -
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Oseltamivir total synthesis
Addition of bromine gives halolactonization product 6 and after replacement of the Bcz protective group by a BOC protective group in 7 (hydrogenolysis in the presence of Di-tert-butyl dicarbonate) a carbonyl group is introduced in intermediate 8 by catalytic Ruthenium(IV) oxide and sacrificial catalyst Sodium periodate. -
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BOC
Di-tert-butyl dicarbonate (abbreviated as "Boc", "BOC" or "t-Boc"), a protecting group in organic and peptide chemistry
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Di-tert-butyl dicarbonate
