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Glycolysis

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Glycolysis (from glycose, an older term for glucose + -lysis degradation) is the metabolic pathway that converts glucose, C6H12O6, into pyruvate, C3H5O3. The free energy released in this process is used to form the high energy compounds, ATP (adenosine triphosphate) and NADH (reduced nicotinamide adenine dinucleotide). Glycolysis is a sequence of ten reactions involving ten intermediate compounds... Read enhanced Wikipedia article

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Muscle Within the voluntary skeletal muscles, the glucose molecule can be metabolized anaerobically in a process called glycolysis which produces two ATP and two lactic acid molecules in the process (note that in aerobic conditions, lactate is not formed; instead pyruvate is formed and transmitted through the citric acid cycle).

Mitochondrion Each pyruvate molecule produced by glycolysis is actively transported across the inner mitochondrial membrane, and into the matrix where it is oxidized and combined with coenzyme A to form CO2, acetyl-CoA, and NADH.

Mitochondrion These energy-rich molecules are produced within the matrix via the citric acid cycle but are also produced in the cytoplasm by glycolysis.

Lactic acid fermentation Glycolysis produces 2 molecules of ATP, reduces 2 molecules of NAD+ to NADH, and creates 2 three-carbon molecules of pyruvate.

Oxidative phosphorylation Glycolysis produces only 2 ATP molecules, but somewhere between 30–36 ATPs are produced by the oxidative phosphorylation of the 10 NADH and 2 succinate molecules made by converting one molecule of glucose to carbon dioxide and water.

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Muscle Within the voluntary skeletal muscles, the glucose molecule can be metabolized anaerobically in a process called glycolysis which produces two ATP and two lactic acid molecules in the process (note that in aerobic conditions, lactate is not formed; instead pyruvate is formed and transmitted through the citric acid cycle).

Human mitochondrial genetics Because they provide 36 molecules of ATP per glucose molecule in contrast to the 2 ATP molecules produced by glycolysis, mitochondria are essential to all higher organisms for sustaining life.

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Anaerobic exercise Anaerobic glycolysis uses glucose inefficiently, and produces by-products such as lactic acid that are thought to be detrimental to muscle function; this limits activity based predominantly on anaerobic glycolysis to about 2 minutes.

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Ackee Beta oxidation normally provides the body with ATP, NADH and acetyl CoA which is used to supplement the energy produced by glycolysis.

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Metabolic pathway In times of excess lipid or protein energy sources glycolysis may run in reverse (gluconeogenesis) in order to produce glucose 6-phosphate for storage as glycogen or starch.

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Lactate dehydrogenase It converts pyruvate, the final product of glycolysis to lactic acid when oxygen is absent or in short supply, and it performs the reverse reaction during the cori cycle in the liver.

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Malonyl-CoA decarboxylase deficiency In this condition, the cells, to make ATP, are forced to increase glycolysis which produces lactic acid as a by-product.

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Cori cycle In the beginning of muscular activity, glycolysis produces pyruvic acid that is converted to acetyl CoA which is metabolized in the citric acid cycle to make ATP through the use of the electron transport chain.

run in :

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Metabolic pathway In times of excess lipid or protein energy sources glycolysis may run in reverse (gluconeogenesis) in order to produce glucose 6-phosphate for storage as glycogen or starch.

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Metabolic pathway In times of excess lipid or protein energy sources glycolysis may run in reverse (gluconeogenesis) in order to produce glucose 6-phosphate for storage as glycogen or starch.

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Metabolic pathway In times of excess lipid or protein energy sources glycolysis may run in reverse (gluconeogenesis) in order to produce glucose 6-phosphate for storage as glycogen or starch.

generates :
net and FADH2.

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Adenosine triphosphate Glycolysis generates a net two molecules of ATP through substrate phosphorylation catalyzed by two enzymes: PGK and pyruvate kinase.

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Chemiosmosis The reduced molecules NADH and FADH2 are generated by the Krebs cycle and glycolysis.

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    Glycolysis

    See also: Gluconeogenesis, which carries out a process wherein glucose is synthesized rather than catabolized. Glycolysis (from glycose, an older term for glucose + -lysis degradation) is the metabolic pathway that converts glucose, C6H12O6, into pyruvate, C3H5O3-.
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    Category:Glycolysis

    Metabolic pathways
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    Cellular respiration

    Glycolysis is a metabolic pathway that is found in the cytoplasm of cells in all living organisms and is anaerobic, or doesn't require oxygen.
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    Citric acid cycle

    Other relevant reactions in the pathway include those in glycolysis and pyruvate oxidation before the citric acid cycle, and oxidative phosphorylation after it.
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    Enolase

    Enolase, also known as phosphopyruvate dehydratase, is a metalloenzyme responsible for the catalysis of 2-phosphoglycerate (2-PG) to phosphoenolpyruvate (PEP), the ninth and penultimate step of glycolysis.
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    Pyruvate kinase

    Instead, it is converted to glucose in a series of gluconeogenesis reactions that are mostly (but not exactly) the reverse sequence of glycolysis.
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    Cori cycle

    While there is a gain of 2 moles of ATP in the anaerobic glycolysis of glucose, there is a cost of 6 moles of ATP in the gluconeogenesis part of the cycle.
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    Adenosine triphosphate

    Glycolysis generates a net two molecules of ATP through substrate phosphorylation catalyzed by two enzymes: PGK and pyruvate kinase.
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    Metabolism

    Once inside, the major route of breakdown is glycolysis, where sugars such as glucose and fructose are converted into pyruvate and some ATP is generated.
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    Biochemistry

    These techniques allowed for the discovery and detailed analysis of many molecules and metabolic pathways of the cell, such as glycolysis and the Krebs cycle (citric acid cycle).

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Glycolysis