Finding:

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   Tamoxifen

   Tamoxifen is an orally active selective estrogen receptor modulator (SERM) that is used in the treatment of breast cancer and is currently the world's largest selling drug for that purpose. ... A significant number of tamoxifen treated breast cancer patients experience a reduction of libido.
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   Oncotype DX

   Oncotype DX analyzes a panel of 21 genes within a tumor to determine a Recurrence Score. ... A multigene assay to predict recurrence of tamoxifen-treated, node-negative breast cancer.
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   Cancer

   Once diagnosed, cancer is usually treated with a combination of surgery, chemotherapy and radiotherapy. ... In this trial, which studied almost 20,000 women, raloxifene had fewer side effects than tamoxifen, though it did permit more DCIS to form.
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   V. Craig Jordan

   Tamoxifen (ICI46,474) as a targeted therapy to treat and prevent breast cancer. ... Osipo, C., Gajdos, C. and Jordan, V.C. (2005) Reversal of tamoxifen resistant breast cancer by low dose estrogen therapy.
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   Breast cancer

   The IBIS trial found benefit from tamoxifen. ... Patients whose cancer cells are positive for HER2/neu have more aggressive disease and may be treated with trastuzumab, a monoclonal antibody that targets this protein.
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   Somatic evolution in cancer

   Tamoxifen in the treatment of breast cancer. ... ↑ Taplin ME, Bubley GJ, Ko YJ, Small EJ, Upton M, Rajeshkumar B, Balk SP: Selection for androgen receptor mutations in prostate cancers treated with androgen antagonist.
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   Breast cancer treatment

   Any combination of systemic treatments may be used to treat breast cancer. ... Tamoxifen is typically given to premenopausal women to inhibit the estrogen receptors
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   Colorectal cancer

   In contrast,there is evidence that exogenous estrogens such as hormone replacement therapy (HRT), tamoxifen, or oral contraceptives might be associated with colorectal tumors. ... Gastric carcinoma · Signet ring cell carcinoma · Gastric lymphoma (MALT lymphoma) · Linitis plastica
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   Immunohistochemistry

   In both cases, the tissue is treated to rupture the membranes, usually by using a kind of detergent such as Triton X-100. ... One of the first therapies was the antiestrogen, tamoxifen, used to treat breast cancer.
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    Endometrial polyp

    "Asymptomatic Endometrial Polyps: What Is the Likelihood of Cancer?". ... "A randomised controlled trial of prophylactic levonorgestrel intrauterine system in tamoxifen-treated women".

Explore the following pages on Powerset:

• Tamoxifen,
• Oncotype DX,
• Cancer,
• V. Craig Jordan,
• Breast cancer,
• Somatic evolution in cancer,
• Breast cancer treatment,
• Colorectal cancer,
• Immunohistochemistry,
• Endometrial polyp