Finding:

1. close

   Oncolytic virus

   Efforts to treat cancer through immunization or deliberate infection with a virus began in the mid 20th century. ... During the 1960s, promising research included poliovirus, adenovirus, Coxsackie virus, and others.
2. close

   Experimental cancer treatment

   Johanna Budwig proposed a diet therapy claimed to treat cancer. ... "Current developments in adenovirus-based cancer gene therapy".
3. close

   Gene therapy

   This vector system has shown real promise in treating cancer and indeed the first gene therapy product to be licensed to treat cancer is an adenovirus.
4. close

   Adenoviridae

   There are no antiviral drugs to treat adenoviral infections, so treatment is largely directed at the symptoms (such as acetaminophen for fever). ... See Adenovirus infection
5. close

   Adeno-associated virus

   Usually, especially in the presence of adenovirus, the longer intron is preferred, so the 2.3-kb-long mRNA represents so-called major splice. ... Clinical trials using an AAV2-based vector to treat haemophilia B seem to indicate that targeted destruction of transduced cells may be occurring.
6. close

   W. Roy Smythe

   While training there, he worked in the first laboratory in the country to use a common cold virus, the adenovirus, to transfer genes to treat cancer, and was the lead author on the first paper describing the use of adenoviral based gene therapy to treat cancer models in the laboratory (Cancer Research, April 1994 15;54(8):2055-9).
7. close

   Gallbladder cancer

   Mutant Adenovirus based treatment is under investigation by several researcher and a company has even got license to use a mutant of Adenovirus (Onyx-15) to cure cancer.
8. close

   Survivin

   Using an adenovirus vector for wild-type p53, human ovarion cancer cell line 2774qw1 (which expresses mutant p53) was transfected. mRNA levels of survivin were analyzed by real-time quantitative PCR (RT-PCR) and showed time-dependent downregulation of survivin mRNA levels when the cells were infected with wild-type p53. ... Anti-androgen Therapy using Flutamide to treat Androgen-dependent Prostate Cancer
9. close

   Human papillomavirus

   ↑ Vaccination to prevent and treat cervical cancer Hum Pathol. ... DNA virus: Adenovirus
10. close

    Onyx-15

    ↑ Definition of ONYX-015 - National Cancer Institute Drug Dictionary ... An adenovirus mutant that replicates selectively in p53-deficient human tumor cells.

Explore the following pages on Powerset:

• Oncolytic virus,
• Experimental cancer treatment,
• Gene therapy,
• Adenoviridae,
• Adeno-associated virus,
• W. Roy Smythe,
• Gallbladder cancer,
• Survivin,
• Human papillomavirus,
• Onyx-15